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Page 1
Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors.
ACS Med Chem Lett. 2020 Feb 19;11(4):521-527. doi: 10.1021/acsmedchemlett.9b00631. eCollection 2020 Apr 9.
ACS Med Chem Lett. 2020.
PMID: 32292559
Free PMC article.
Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD.
Ratia KM, Shen Z, Gordon-Blake J, Lee H, Laham MS, Krider IS, Christie N, Ackerman-Berrier M, Penton C, Knowles NG, Musku SR, Fu J, Velma GR, Xiong R, Thatcher GRJ.
Ratia KM, et al.
Biochemistry. 2023 Feb 21;62(4):923-933. doi: 10.1021/acs.biochem.2c00655. Epub 2023 Feb 6.
Biochemistry. 2023.
PMID: 36746631
Free PMC article.
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Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability.
Lazzara PR, David BP, Ankireddy A, Richardson BG, Dye K, Ratia KM, Reddy SP, Moore TW.
Lazzara PR, et al. Among authors: ratia km.
J Med Chem. 2020 Jun 25;63(12):6547-6560. doi: 10.1021/acs.jmedchem.9b01074. Epub 2019 Nov 14.
J Med Chem. 2020.
PMID: 31682434
Free PMC article.
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Discovery of Nonlipogenic ABCA1 Inducing Compounds with Potential in Alzheimer's Disease and Type 2 Diabetes.
Ben Aissa M, Lewandowski CT, Ratia KM, Lee SH, Layden BT, LaDu MJ, Thatcher GRJ.
Ben Aissa M, et al. Among authors: ratia km.
ACS Pharmacol Transl Sci. 2021 Jan 5;4(1):143-154. doi: 10.1021/acsptsci.0c00149. eCollection 2021 Feb 12.
ACS Pharmacol Transl Sci. 2021.
PMID: 33615168
Free PMC article.
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